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Latent Variable Modeling for Developing Neuroprosthetic Devices
Application
A high-performing neural decoder that reconstructs spiking data from local field potentials to analyze neural recordings for developing neuro-prosthetic devices.
Key Benefits
Capable of augmenting local field potential to overcome perturbations in data.
Improved decoding stability with high accuracy.
Potential to lead to the development...
Published: 2/13/2025
Updated: 8/5/2024
Inventor(s): Brianna Karpowicz, Chethan Pandarinath, Yahia Ali, Marc Slutzky, Robert Flint, Bareesh Bhaduri
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Antisense Restoration of ELAVL3 for Neurological Diseases
Application
Antisense therapeutics targeting ELAVL3 expression for neurodegenerative disorders.
Key Benefits
Antisense approach for restoring protein levels and function of ELAVL3 and TDP-43.
Preclinical data show the ability of several ELAVL3-targeting ASOs to restore protein expression via in vitro experiments.
Potential to be a new medicine...
Published: 2/13/2025
Updated: 8/5/2024
Inventor(s): Zachary X McEachin
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Implanted Passive Pressure Sensor Interrogated with (Ultra)-Sound (iPPSIS)
Application
Easy-to-use, short and long-term, minimally invasive, MR-safe approach for directly measuring the variation of intracranial pressure.
Key Benefits
A minimally invasive device that is compatible with MRI imaging for quantitatively measuring intracranial pressure.
A prototype has been developed showing the ability to measure shunt pressure...
Published: 2/13/2025
Updated: 8/5/2024
Inventor(s): David Myers, Nicholas Au Yong, Brooks Lindsey, Cecilia Alessandra Luna, Saeyoung (Sunny) Kim, Bowen Jing
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Multi-Modal Sensing Platform for Diagnosing Depression and Schizophrenia
Application
A multi-sense deep learning platform and interview protocol used for detection and assessment of depression and schizophrenia.
Key Benefits
Automated and remote mental illness assessment without the need for self-reporting or clinical observation.
Improved disease tracking for patients and clinicians.
A more objective classifier and...
Published: 2/13/2025
Updated: 8/5/2024
Inventor(s): Gari Clifford, Robert Cotes, Mina Boazak, Zifan Jiang, Seyed Salman Seyedi, Ali Bahrami Rad
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Novel Therapeutic Target for Fragile X Syndrome and Neurodevelopmental Disorders
Application
Salvianolic acid C for treating Fragile X Syndrome (FXS).
Key Benefits
New therapeutic drug candidate for the treatment of FXS.
Preliminary data in the laboratory in organoids treated with the drug showed rescued cell phenotypes known to be associated with the disease in humans.
Potential to treat other neurodevelopmental disorders.
Market...
Published: 2/13/2025
Updated: 8/5/2024
Inventor(s): Peng Jin, Chuan He, Zhongyu Zou
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The CaRE Course: CaREgiving While Black
Application
The CaRE Course is a curriculum to develop caregiving mastery of people living with dementias (PLWD) while understanding, acknowledging, and addressing the influence of race, culture, and disparities on caregivers’ mental health, medical, spiritual, and safety needs during the COVID-19 pandemic.
Key Benefits
Augments caregiver's...
Published: 2/13/2025
Updated: 8/5/2024
Inventor(s): Fayron Epps, Kenneth Hepburn, Carolyn Clevenger, Stephanie Bennett
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Faith-based Home Activity Toolbox (HAT)
Application
Set of interventional activity tools designed to incorporated faith-based principles to improve the quality of life of individuals living with or family members caring for persons with moderate to severe Alzheimer Disease or related dementias.
Key Benefits
Provides relief from anxiety.
Reduced behavior disturbances.
Improved quality...
Published: 2/13/2025
Updated: 8/5/2024
Inventor(s): Fayron Epps
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Dementia-Friendly Online Worship Services
Application
Religious (Christian) service videos available through a public online platform that are tailored to support the well-being of caregivers and family members of persons living with dementia (PLWD).
Key Benefits
Provides relief from anxiety.
Reduced behavior disturbances.
Improved quality of life for individuals living with dementia...
Published: 2/13/2025
Updated: 8/5/2024
Inventor(s): Fayron Epps
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Machine Learning for Neurodegenerative Disease Diagnosis and Monitoring
Application
A machine learning classification model incorporating biomarkers for detecting Parkinson's disease.
Key Benefits
The image processing methods are simple to use, and the processing pipeline is fully automated.
The method is novel and customized to address the practical requirements of clinical and research imaging.
Market Summary
Parkinson’s...
Published: 2/13/2025
Updated: 8/5/2024
Inventor(s): Daniel Huddleston, Babak Mahmoudi
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Flumazenil for Treatment of CNS Symptoms in Myotonic Dystrophy
Application
A class of drugs that inhibit molecules responsible for the severe nervous system complications associated with myotonic dystrophy.
Key Benefits
Potentially the first medication for treating the severe nervous system symptoms associated with myotonic dystrophy by targeting GABRG2.
Transdermal and oral administration.
May drive the...
Published: 2/13/2025
Updated: 8/5/2024
Inventor(s): Gary Bassell, Andrew Jenkins, David Rye, Eric Wang, Maurice Swanson, Lyndon Lien
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